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Augmenting CNS glucocerebrosidase activity as a therapeutic strategy for parkinsonism and other Gaucher-related synucleinopathies

-Caryophyllene from clove extract shows potent antimicrobial activity against Helicobacter pylori , significantly reducing bacterial load both in vitro and in vivo

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As detailed later, both alkaloids are believed to drive the opioid-like effects of kratom, with 10-fold lower and 10-fold higher potency than morphine, respectively