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Our previous animal experiments also demonstrated that acute IOP elevation upregulates inflammation protein marker (IL-1, TLR-4, and TNF-) expression in the rat retina [93]

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doi: 10.1038/srep32206 (2016)

According to (Lobo et al., (2010) adipose tissue is an important producer of several hormones, growth factors, and cytokines (such as leptin, adipsin, resistin, angiotensinogen, TNF-, plasminogen activator inhibitor type-1, and IL-6)

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Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinsons Disease