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Vitamin C also helps regenerate glutathione back to its active form to enhance its power and long-term effects, while glutathione protects cells from oxidative damage by recycling Vitamin C

These roles are thought to be linked to its influence on signaling pathways such as those involving Vascular Endothelial Growth Factor (VEGF) and Transforming Growth Factor beta (TGF-)

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The extinction coefficient for the GST moiety alone is ~ 1.5, i.e., 1.00 A 280 = ~ 0.6 mg/ml protein, although the extinction coefficient for the fusion protein will depend partially on the absorbance characteristics of the target protein