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Description
2010;5(4):e10305
Inflammatory cytokines associated with degenerative disc disease control aggrecanase-1 (ADAMTS-4) expression in nucleus pulposus cells through MAPK and NF-B
Scientists have proven NR's effectiveness through multiple dose-finding studies
Doses over 150 mcg are most effective
The exact timing depends on the patients needs, like how severe the deficiency is and how well they absorb the vitamin
Avoid this treatment if you have diabetic ketoacidosis or Type 1 diabetes
