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For the Q260A mutant, each MraY dimer was detected in a complex with between 14 molecules of endogenous lipid I, indicating that the ligands can bind to MraY at other sites besides the canonical catalytic sites

Next, we repeated the pulse-chase experiment in worms

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Additionally, microbial lipase production is widely established at scale, enabled by rapid growth on affordable media (Rmili et al

Therefore, we generally advise our obese patients to focus on achieving a healthier weight through diet and exercise, or potentially bariatric surgery, depending on the severity of obesity