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When high concentrations of glucose and free fatty acids (FFAs) enter cells, they are metabolized into pyruvate and acetyl-CoA

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Among all the available markers of lipid peroxidation, F2-Isoprostanes is well suited as a biomarker for the following reasons: (i) In vivo formation of isoprostane increases as a function of lipid peroxidation

Cells and mitochondrial viability assay The effect of the prepared dendrimeric constructs on the viability of rat hepatocytes and isolated mitochondria was evaluated using the MTT assay (30)

David CC, Jacobs DJ (2014) Principal component analysis: a method for determining the essential dynamics of proteins

PAS (Pernicious Anaemia Society) Based in Wales, UK