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Potassium is a clear example of this problem
Cloning of the rat alpha 1C-adrenergic receptor from cardiac myocytes
CJC 1295 mimics natural GHRH, keeping GH levels steady over timeespecially with the DAC version, which extends its half-life

The authors claimed that these variants not only displayed increased BBB crossing, but also of greater importance maintained the neurotropism, paving the translational potential of neurological disorders treatment

A., Hammer, R
Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins
