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The mechanisms by which LA reduces liver fat content in HFD animals may be related to suppressing oxidative stress and lipid peroxidation, improving mitochondrial dysfunction, inhibiting insulin resistance, and regulating some related factors or genes (such as ROS-scavenging enzyme genes) to inhibit excessive fat synthesis in the liver

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Os Experimental & Molecular Medicine .2024

J Clin Invest 2001;106:1095103

Zhang, Y., Ling, J., Yuan, C., Dubruille, R

For systemic nerve conditions and inflammation, ARA-290's mechanism may prove more relevant
