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Injection site reactions including temporary redness, swelling, or itching occur occasionally

PMID: 27075906 [2] Sukumar N, Rafnsson SB, Kandala NB, Bhopal R, Yajnik CS, Saravanan P

Jama , 302 (19), 2119-2126

We review current knowledge of skin copper/zinc superoxide dismutase including recent studies in an attempt to contribute to solving the question of its remaining unexplained functions

Multiple genome-wide association studies have found single nucleotide polymorphisms in TNFSF15 that are associated with an increased risk of CD and UC ( Based on the human genetic data and the promise of TL1A inhibition in non-clinical models, as well as the established efficacy of TNF inhibitors in IBD, Amgen designed AMG 966, a TNF/TL1A bi-specific immunoglobulin therapeutic candidate