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(Figure 4D) Neutrophils Release NETs NETs represent a highly conserved antimicrobial defense mechanism employed by neutrophils, characterized by an extracellular network composed of DNA and proteins that effectively capture and eliminate pathogens, thereby preventing their dissemination 7 (Figure 4E)

Fresh SP@M was recommended to be prepared before use

5 As a result, a large-scale model would be required to determine their safety and effective dose, optimum treatment absorption, duration, and bioavailability

Hormonal medications (e.g., birth control pills, thyroid hormone) for contraception or hormone replacement, etc

Approximately 30% of persons with MDD have substantial neuroinflammation in the CNS, which is associated with increased symptom intensity and resistance to standard treatments [47,63]
