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Lombardi G, Di Somma C, Grasso LF, Savanelli MC, Colao A, Pivonello R

397 In a Phase II trial (NCT02420314) for advanced NSCLC, Ascorbate combined with Carboplatin and Paclitaxel inhibited tumor growth through HO generation, iron modulation (higher transferrin linked to improved PFS), and immune activation (4.2-fold increase in CD8 + T cells), achieving a 34.2% response rate and a 12.8-month median OS

Systemic glutathione deficiency in symptom-free HIV-seropositive individuals

Lancet 395(10224):565574 Wang Z, Xu X (2020) scRNA-seq profiling of human testes reveals the presence of the ACE2 receptor, a target for SARS-CoV-2 infection in spermatogonia, Leydig and Sertoli cells

By preserving muscle integrity, LCLT provides a vital safety net for those slowly rebuilding their physical capacity

Each symptom was scored on a 4-point scale (0 = absent, 1 = infrequent, 2 = frequent, 3 = constant), yielding a total Symptom Score (SS) ranging from 0 to 30, reflecting overall symptom burden and impact on QoL