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An increasing number of patients treated with novel antidiabetic drugs, including glucagon-like-peptide-1 receptor agonists (GLP-1RA), dual glucose-dependent insulinotropic polypeptide receptor agonists and sodium-glucose cotransporter-2 (SGLT2) inhibitors, are presenting in the perioperative...

This article examines clinical evidence for combination therapy, safety profiles, and how genetic predispositions in GLP-1 and glucose metabolism pathways may info

Metabolic Engineering activates the same pathway naturally without the side effects.

Yet the identity of the downstream signalling events mediated by these peptides remain to be elucidated
