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Description
PNS can effectively improve clinical outcomes and multiple functional indicators by enhancing meningeal lymphatic drainage, inhibiting inflammatory responses, regulating apoptosis-related pathways (such as inhibiting Caspase-3 and upregulating Bcl-2), protecting the integrity of the blood-brain barrier, and promoting nerve remodeling

According to the MCC algorithm, VEGFA, CASP3, JUN, HIF1A, STAT3, EGFR, TNF, IL6, SRC, MTOR are the top 10 genes

NeuroReport 33(13):569576 Mercado NM et al (2022) Traumatic brain injury alters the gut-derived serotonergic system and associated peripheral organs
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R., Hand, J

(b) clinical and biochemical improvement when the drug is discontinued
