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Zinc monotherapy is effective in Wilsons disease patients with mild liver disease diagnosed in childhood: a retrospective study

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The resulting lack of IDO2 activity hinders tryptophan conversion to kynurenine

Additionally, the lack of methylation impairs the brain's ability to clear out neurotoxic metabolites, allowing them to accumulate and disrupt neural signaling

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Nausea may emerge, usually mild and often resolving within 1-2 weeks as your body adapts