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23 Furthermore, it was shown that vitamin C can play a role as a carcinostatic agent by inhibiting angiogenesis via decreasing the expression of angiogenesisrelated genes such as basic fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF) and matrix metallopeptidase 2 (MMP2)

Transcriptomic and metabolomic analyses have shown that PHGDH, PSAT1 and PSPH are highly expressed in GBM cells, and their expression levels are closely associated with poor patient prognosis (6466)

For example, germinal vesicle (GV) mouse oocytes were treated with different H 2 O 2 concentrations during in vitro maturation displayed concentration dependent increased incidences of misaligned chromosomes, spindle abnormalities, and aneuploidy (75)

Metabolism, 57 (5), 712-717