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The safety of BSO with chemotherapy has already been established in patents with other tumor types ( 27, 28 ), and strengthens the rationale to pursue this approach in patients with PDAC

Am J Respir Cell Mol Biol 41:509515 Corti A, Franzini M, Paolicchi A, Pompella A (2010) Gamma-glutamyl transferase of cancer cells at the crossroads of tumor progression, drug resistance and drug targeting

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Yoo S-E, Chen L, Na R, Liu Y, Rios C, Van Remmen H et al (2012) Gpx4 ablation in adult mice results in a lethal phenotype accompanied by neuronal loss in brain