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Comprehensive assessment of pesticide use patterns and increased cancer risk

Furthermore, -syn exacerbates mitochondrial dysfunction by binding to VDAC, where it partially obstructs the pore and thereby impairs the transport of ATP/ADP and other metabolites

Conversely, hyperglycemia contributes to the genesis of advanced glycation end products (AGEs), oxidative stress, and inflammation, thereby exacerbating cardiac dysfunction and provoking structural remodeling [612]

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