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Over the past few years, multifactorial pre-clinical models that consider two or more perturbations to mimic human HFpEF have been developed

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Two important enzymes, carnitine palmitoyl transferase I (CPT I) and carnitine palmitoyl transferase II (CPT II), facilitate the transfer of acyl groups between acyl-CoA and carnitine

Acknowledgments The authors thank the co-workers of the Institute of Animal Nutrition and the co-workers of the experimental station of the Friedrich-Loeffler-Institut in Braunschweig for their great support, as well as all other members of the MitoCow team

Kara Fitzgerald: Yes

These results indicated that inhibition of CPT1 restored the lipoprotein profiles toward normal homeostasis in accordance with the finding in Fig