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223 It is important to highlight that these enzymatic reactions occur in an anaerobic environment, and the introduction of the hydroxy group occurs via hydration and not oxidation

In contrast to loss of FOXO4, FOXO4-DRI does not sensitize healthy cells to acute DNA damage (Fig

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In addition, under conditions of reduced oxygen tension guanosine can be modified to 2,6-diamino-4-hydroxy-5-formamidopyrimidine (FapydG), which together with 8-OHdG are the most abundantly formed oxidized forms of DNA bases

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The effects of hormonal changes on sperm DNA integrity in oligoasthenoteratospermia individuals: A case-control study