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We next assessed the effects of HPL on the expression of ER, ER, Ggt1, and Anpep using western blot assays (Figures 4C,D and see Supplementary Tables S11 and Supplementary Figure S1)
Challenges include achieving adequate statistical power despite slow disease progression or subtle intervention effects, managing high variability in patient responses, and defining appropriate patient stratification criteria based on complex baseline microbial or metabolic features (63, 168)
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Positive result (+) and negative result () and weak positive result (w)
