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However, PSPH ser/gly pathway enzyme genetic aberrations are not acknowledged as important drivers of GBM because of the close proximity of EGFR (chr7:5501901755211628) to PSPH (chr7:5601105156051604), which is a common driver oncogene in GBM [47,48,49]
Lactate-modulated induction of THBS-1 activates transforming growth factor (TGF)-beta2 and migration of glioma cells in vitro
[DOI] [PMC free article] [PubMed] [Google Scholar] Foyer CH, Baker A, Wright M, Sparkes I, Mhamdi A, Schippers JHM, Van Breusegem F
In evaluating head injury specifically, neurosurgeons utilize a scale, the Glasgow Coma Scale (GCS), to assess severity
