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This review systematically describes the multi-target mechanisms of SIRT1 in MASLD pathogenesis through its regulation of critical factors, including peroxisome proliferator-activated receptor gamma coactivator 1-, Forkhead Box O, and nuclear factor kappa-light-chain-enhancer of activated B cells, which govern hepatocyte lipid remodeling, mitochondrial quality control, autophagyendoplasmic reticulum stress balance, and Kupffer cell/T cell polarization

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Effect of high-dose vitamin C infusion in a glucose-6-phosphate dehydrogenase-deficient patient

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Examples of this include GADD34 (PPP1R15A) 443 and CHOP

References 1 AlvarezS