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Sellers, R
Biochem Biophys Res Commun (2021) 581:611

Patients with high levels of EOC MRD have a significantly inferior EFS compared with other patients.[134,135,139] In one study by the Dutch Children's Oncology Group, patients with low but detectable EOC MRD ( 5%) at EOI had a poor prognosis

Sadoulet, P

Int J Dev Neurosci 23:171182

Research found that a decreased network response to stimulation in both excitatory and inhibitory circuits of the sensory cortex of Nlgn4 knock-out animals as compared to wild-type controls, and a decreased excitation-inhibition ratio, suggesting that Nlgn4 is involved in the regulation of excitatory and inhibitory circuits and contributes to a balanced circuit response to stimulation (88).Another study reports, Nlgn4 knockout disrupts GABAergic synaptic transmission and oscillatory activity in the hippocampus and causes deficits in social interaction
