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Additionally, the Keap1/Nrf2/HO-1 signaling pathway, which is activated by antioxidants such as tectorigenin, plays a role in reducing oxidative stress and inflammation in asthma, suggesting a potential therapeutic synergy with Trx1 [105]

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10.18240/ijo.2022.08.01 88 LianQ.YanS.YinQ.YanC.ZhengW.GuW.et al (2021)

58,672 Their collective efforts have established that the EpOMEs are protoxicants that require activation by sEH to the DiHOMEs

Cundy T, Dissanayake A