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[DOI] [PMC free article] [PubMed] [Google Scholar] 51.Miyamoto HD, Ikeda M, Ide T, Tadokoro T, Furusawa S, Abe K, Ishimaru K, Enzan N, Sada M, Yamamoto T, Matsushima S, Koumura T, Yamada KI, Imai H, Tsutsui H

Surprisingly, another meta-analysis revealed that the expression of enzymes involved in the mitochondrial folate cycle better correlates with sensitivity to methotrexate than the cytosolic folate cycle [104]
Moreover, the type of induced stress also resulted in sex-dependent differences in oxaliplatin-induced peripheral sensory neuropathy (Staurengo-Ferrari et al., 2021)

Science 2019, 365 (6448), 7679
They have a wide range of subcellular localization: SOD1 is located in the cytoplasm, while SOD2 (MnSOD) is found in the mitochondria, and SOD3 (ECSOD) is distributed in the extracellular matrix [66]

Melanin is what gives pigment to hair and eyes and colour to the skin