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Interaction with Carbapenem Antibiotics: The concomitant use of INN and carbapenem agents is not recommended (see Carbapenem Antibiotics under Interactions)

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The use of meldonium in pulmonary hypertension-induced right ventricular failure and inflammation-induced left ventricular systolic dysfunction, like those seen in COVID-19, shows that meldonium alone or in combination with anti-inflammatory drugs improves heart function in cases of excessive inflammation and cytokine storm, according to a study conducted on animals [34]

Lee SD, Huang CY, Shu WT, Chen TH, Lin JA, Hsu HH et al (2006) Pro-inflammatory states and IGF-I levels in ischemic heart disease with low or high serum iron