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The regulation of MPC by androgens/AR promotes the direct flow of glycolytic flux into mitochondria, fueling TCA metabolism and subsequently increasing OXPHOS and lipogenesis in PCa cells

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The inflammatory response following MI also triggers coronary microvascular endothelial dysfunction, impairing vasodilation in response to increased oxygen demand and potentially leading to coronary microvascular spasm and inadequate myocardial perfusion (235)

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[59] Ames BN, Liu J.Ann N Y Acad Sci

This is confirmed and studied in depth in a complementary study reported in a manuscript co-submitted with this one (Kumar et al, co-submitted)