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Intriguingly, recent investigations have demonstrated that irisin upregulates the expression of TFAM (mitochondrial transcription factor A) through the activation of the SIRT1/PGC-1 signaling pathway, thereby enhancing mitochondrial metabolism and mitigating microglial activation 18

A compound called homocysteine thiolactone forms when homocysteine incorrectly binds to lysine residues of cellular proteins, leading to damage in the cell structure

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