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[DOI] [PMC free article] [PubMed] [Google Scholar] 112.Qu XaD R
Mitochria produce ROS during energy generation but excess ROS directly damages mitochondrial DNA and disrupts energy production systems
Apoferritin, the iron-depleted form of ferritin, is composed of 24 self-assembled subunits that form a spherical nanocage with a diameter of approximately 12 nm, featuring an internal cavity of 8 nm capable of encapsulating drugs, thereby constituting a ferritin drug carrier (FDC)
The underlying mechanism includes that glycine abundance is elevated to inhibit glutathione reductase and thereby ROS level is increased 73
An experimental study in the rat
