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To fine-tune the redox homeostasis that can either prohibit the damage by oxidative distress or maintain the physiologic ROS to sustain normal cellular processes, organisms have evolved a complex antioxidant defense system consisting of both enzymatic and non-enzymatic scavengers

N., Jensen, G

The results of animal studies further show that esculetin can improve the oxidative stress caused by ischemia-reperfusion

PubMed Rhim HC, et al

10.1016/j.foodres.2020.109409 [DOI] [PubMed] [Google Scholar] 33.Liu A, Gong Z, Lin L, Xu W, Zhang T, Zhang S, et al