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Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-label, cluster-randomised trial

CagriSema produced mean weight loss of 13.7% at 68 weeks compared to 3.4% with placebo, and 73.5% of CagriSema-treated participants achieved HbA1c of 6.5% or below compared to 15.9% with placebo

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Peripheral transporters play as much an important role in psychotropic pharmacokinetics as do the BBB transporters in delivering to and clearing psychotropics from the brain