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This research was supported by a Korea Basic Science Institute (National Research Facilities and Equipment Center) grant funded by the Ministry of Education (grant No

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Concurrently, radiationtriggered sphingomyelinase activation disrupts membrane integrity, synergizing with receptorinteracting protein kinase 3 (RIPK3)/mixed lineage kinase domainlike pseudokinase (MLKL)mediated necroptosis to form an interconnected cell death network [108]

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This latter process allows the remnant to be taken up via the chylomicron remnant receptor, which is a member of the LDL receptor-related protein (LRP) family