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An RCT (n = 62) ranked as level of evidence 1b compared the topical administration of EGCG with placebo on the area surrounding a wound (zonal priming) and the fully formed scar

4-hydroxynonenal induces apoptosis via caspase-3 activation and cytochrome c release

Accessed January 2026.

They serve as models to understand tumor behavior and test therapeutic strategies

Cutillo S
