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All commercial syntheses are based on the concept of a three-component, one-pot reaction of triamino-pyrimidinone with a three-carbon compound of variable structure (e.g., halogen derivatives of propanal, propanone, and propane) and p -aminobenzoyl-L-glutamic acid to yield folic acid

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[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Wong V.W.-S., Ekstedt M., Wong G.L.-H., Hagstrm H

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pointed out that inositol, omega-3 fatty acids, vitamin D, and resveratrol increase hormonal balance and insulin sensitivity in PCOS patients [65]