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For example, certain mutations in the c-MET receptor can cause conformational changes that prevent both type 1 and type 2 inhibitors from binding effectively, limiting their therapeutic benefit

For culture, all cells were incubated in RPMI 1640 medium (Gibco, Thermo Fisher Scientific) supplemented with 10% fetal bovine serum (TYCOTO

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CRY1/2 Selectively Repress PPAR and Limit Exercise Capacity

Inhibition of histone deacetylase in utero causes sociability deficits in postnatal mice
