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Large-scale randomized controlled trials employing standardized polyphenol preparations and prioritizing objective indicators of mucosal healing and clinical outcomes are essential to definitively establish the therapeutic role of polyphenols in CD management

Neuropharmacology 165:107919 Li W, Ali T, Zheng C, He K, Liu Z, Shah FA et al (2022) Anti-depressive-like behaviors of APN KO mice involve Trkb/BDNF signaling related neuroinflammatory changes

Control experiments were also performed to confirm that compound 102 would not interfere with the dual-luciferase reporter assay system ( Supplementary Figure S10 )

In addition, rat lenses transmit almost all incoming UV-A, which can damage the rat retina (162), suggesting that rats lack UV-A absorbing compounds (32)

J Pediatr 124:229233 Larsson A, Anderson ME (2001) Glutathione synthetase deficiency and other disorders of the gamma-glutamyl cycle

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