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Description
Liver, heart, and quadriceps tissue were snap frozen for acylcarnitine profiling in the Metabolic Core Facility at the University of Pittsburgh/UPMC Childrens Hospital of Pittsburgh as described (58, 59)

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Thus, substantial and mounting evidence supports a direct contributory role of gut microbiota as a participant in CVD pathogenesis, and preclinical studies indicate that the therapeutic targeting of microbial contributors to the TMAO metaorganismal pathway may hold promise as a novel approach for the prevention or treatment of CVD
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