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Animal Model:Wistar rats (male, 200-250 g, spared nerve injury-induced neuropathic pain) [2] Dosage:5 M Administration:bilateral stereotaxic microinjection into rACC

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123 Besides, oxidative stress conditions also increase the innately high IDH1 expression, and IDH1 silencing significantly enhances cell sensitivity to cancer chemotherapy, radiotherapy, and photodynamic therapy by reducing NADPH

Additionally, new modifications to the ketogenic diet, which do not necessarily generate ketosis, are also effective in children with intractable epilepsy [46]

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Its found naturally in animal products, but also added to certain foods and is available as an oral supplement or injection