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10.1016/j.ejphar.2022.174742 143 Lopes de OliveiraG

This distribution of metabolic labor prevents overtaxing a single organ system, provided the patient does not have pre-existing liver or kidney disease

L.BurlingameB.DeanT.Fairweather-TaitS.et al (2017)

However: They are not first-line treatments for acute emergencies

The metabolic heterogeneity of cancer cells arises from a diverse range of factors, such as genetic mutations and the tumor microenvironment (5,7)

doi: 10.1038/ng.3039