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Redox Signaling 18, 522555

[DOI] [PMC free article] [PubMed] [Google Scholar] 59.Guney Varal I., Dogan P., Gorukmez O., Dorum S., Akdag A

While mitochondria have their own antioxidant defenses, including mitochondrial SOD, these defenses are often insufficient to neutralize the high levels of ROS produced during oxidative phosphorylation, especially if mitochondrial function is compromised

doi: 10.1111/j.1365-2958.2005.04929.x [DOI] [PubMed] [Google Scholar] 122
Risk factors of vitamin B12 deficiency in patients receiving metformin

As you age, your body produces less estrogen and testosterone, especially during life stages like menopause and andropause
