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Q10A, N14A, or V17A mutation of the N-terminal part of human amylin also significantly increased potency for CTR and/or amylin receptor 1 activation

10.1074/jbc.M802691200 22 ChenJ.ChenC

BMC Vet Res (2017) 13:161

Compared with standard care, the peptide group exhibited 25 % faster epithelial recovery and reduced erythema within 72 hours

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At the same time, using bioinformatics tools to dynamically monitor and analyze gene expression changes and signaling pathway regulations during drug action helps to further validate drug mechanisms of action and optimize drug treatment plans (Alshabi et al., 2019)