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An interesting finding was highlighted by experiments conducted on specific AD mouse models that are unable to synthesize vitamin C on their own (KO-Tg AD)

In addition, C16-carnitine has been shown to regulate the growth, differentiation and nerve regeneration of nerve cells by affecting the palmitoylation of the GAP-43 protein [46]

It could be postulated that hunger-free fasting was more effective than modified fasting in fatty liver management, because 10-20% of the dose may enter the liver during the first 2 hours after administration [13]

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This upregulation leads to an increased expression of lipogenic genes, including sterol regulatory element-binding proteins (SREBP1c) and diacylglycerol acyltransferase-2 (DGAT2), which suggests that miR-370 provides a further point of regulation of this pathway 86