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doi: 10.1186/s40035-021-00271-0 14

The required elements are directly absorbed through the oral mucosa when film is swallowed, skipping the digestion process

Human dosing figures circulating in the research community are either human-equivalent-dose extrapolations from mouse protocols or vendor-driven tablet/capsule suggestions with no primary-source backing

However, while vitamin B12 supplements may help those with neurological function concerns or deficiencies, the evidence isnt strong enough to support its use as a standalone treatment for depression