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There is no evidence that vitamin B12 deficiency occurs as part of the underlying disease process in ME/CFS

BMC Complement Med Ther

The xCT exchanges intracellular glutamate for extracellular cystine, which is reduced to cysteine in the cytosol and ready for GSH synthesis [82,92,93,94,95]

Insulin: Glutathione could potentially interact with insulin, leading to fluctuations in blood sugar levels

Chronic illness as well as long term toxic exposure to xenobiotic overload can not only deplete stores of glutathione but also inhibit its production

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