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Alternatively, GST P1-1 may mediate its effect by sequestering the drug compounds, as recently identified for cisplatin [11]

The contribution of Niemann-Pick SMPD1 mutations to Parkinson disease in Ashkenazi Jews

It is possible that in the knockdown neurons, excessive organelles accumulate at the base of apical dendrites because effective outward organelle trafficking towards the distal area of the dendrite is prevented

This would allow us to further expand our understanding on the pathogenesis of insulin resistance and involvement of the mitochondrial toxicity

For a 5mg vial, using 2.5mL creates a concentration of 2mg/mL (2000mcg/mL)

Additional inclusion criteria were as follows: age between 18 and 65 years (inclusive), a body mass index (BMI) between 18 and 30 kg/m 2 (inclusive) and the ability to read and understand the written consent form, complete study-related procedures and communicate with the study staff
