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In the C26 model, Balb/c or CD2F1 mice undergo body weight loss and muscle wasting, mainly through increased levels of circulating Interleukin-6 (IL-6), with premature death by 1430 days from cell inoculation, according to the individual cell clones (Talbert et al., 2014

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Nilsson et al., 2003)

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Furthermore, studies conducted with buffalo semen samples cryopreserved with 2.5 and 7.5 mM carnitine [96] and human semen samples cryopreserved with L-Carnitine at 5 mmol/L (established optimal concentration) [97] also demonstrated L-Carnitines beneficial effects in preserving sperm quality and enhancing motility during cryopreservation