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Heres why: Energy Production: B12 is essential for converting food into glucose, which provides energy for the body

Theyre tired, achy, or a bit off

And the metabolic endpoint being measured

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Moreover, low levels of B12 reduce the supply of oxygen, which leads to a decrease in the RBC count

The MHRA has issued safety advice regarding metformin and reduced B12 levels, recommending monitoring in people on long-term treatment