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Role of the mucins in pathogenesis of COPD: implications for therapy

As metabolic profiling technologies mature and integrate into clinical practice [133,134,135], the vision of metabolism-informed immunotherapycustomized to the metabolic vulnerabilities of both tumor and immune cellsbecomes increasingly attainable

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Genes that are involved in lipid accumulation are negatively regulated by Nrf2 [87], and this finding supports the relevance of Nrf2 in NAFLD patients

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Annu Rev Biochem 52:711760 Njalsson R, Norgren S, Larsson A, Huang CS, Anderson ME, Luo JL (2001) Cooperative binding of gamma-glutamyl substrate to human glutathione synthetase