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647 Furthermore, lncRNAs partake in the formation of resistance to immunotherapy by modulating diverse molecular pathways within tumor cells, including those related to cell cycle regulation, apoptosis, metabolism, and epigenetic modifications

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This significance is further highlighted by the fact that older age groups are often polymedicated

For example, in hepatoma cells, SLC1A5 mRNA expression was reduced by 2030% and glutamine uptake was attenuated by 40% in c-myc +/ mice and cells in comparison to the levels in c-myc +/+ mice [87]
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Dual pH/light-responsive PEG-PDMAEMA-PNBAE micelles released curcumin at 46.5% under UV light at pH 5.5, protecting PC12 cells from A-induced apoptosis (138)
