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Mechanistically complementary

They are not equivalent in efficacy but serve different roles in weight management

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10.1016/j.tibs.2006.11.006 14 BrachsS.PolackJ.BrachsM.Jahn-HofmannK.ElvertR.PfenningerA.et al (2019)

Preclinical and early clinical research indicates that AOD 9604 may influence lipid metabolism , energy expenditure , and cartilage repair , while displaying a safety profile distinct from full-length hGH.Development as an anti-obesity drug was eventually discontinued due to insufficient efficacy in long-term weight-loss trials

Adherent cells were scrapped, then centrifuged at 4C and 13000 g for 15 min, and the resulting supernatants processed using established protocols.[19] Intracellular levels of 1-MNA and as well as the IS were determined from LC/MS/MS peak areas